icobrain ep helps physicians with the detection of hippocampal sclerosis in patients with intractable (uncontrollable) epilepsy.The icobrain ep software aids the assessment of hippocampal asymmetry and, therefore, aids the detection of hippocampal sclerosis, a common cause of intractable epilepsy.icobrain ep uncovers abnormality patterns by:Comparing hippocampal asymmetry to an age-and-sex matched normative healthy population.Assessing the juxtacortical abnormalities (which can indicate cortical malformations).